A welcoming, South San Francisco, CA Hotel near SFO Airport Come stay at the Comfort Inn & Suites San Francisco Airport North for your next business trip, family vacation or romantic retreat to South San Francisco. Book your perfect Bay Area escape and take advantage of complimentary airport shuttle transportation to and from San Francisco International Airport, an onsite fitness room, business center and an outdoor spa. Our lovely garden courtyard welcomes you on arrival. Wake up to complimentary breakfast, or order a meal from a nearby restaurant, right to your room. Located off Highway 101, the hotel is three miles north of San Francisco International Airport, 12 miles from Fisherman's Wharf and 11 miles from Downtown San Francisco, positioning you perfectly to take advantage of everything the Bay Area offers.